Manchester United have had a calendar year to forget in 2014, with a seventh-place finish in last season’s Premier League (resulting in no European competitions in 2014-15), the midseason firing of David Moyes, and the summer exodus of many veteran players. Tuesday started brightly for the club, as they announced the signing of Argentinian Angel Di Maria from Real Madrid. But later that day, United suffered their most shocking defeat in recent memory: a 4-0 loss to League One Milton Keynes Dons in the second round of the Capital One Cup.

For those who don’t understand how big this loss was for United, imagine a team from one of the NCAA Power Five conferences – particularly one with a high pedigree, like Alabama or Florida State – losing to a Division II school convincingly. After a bright start for United, MK Dons took the lead following an error from Jonny Evans, and never looked back the rest of the night.

Now for United, it’s back to the Premier League, and a visit to Burnley is the first match of Saturday’s slate. The Clarets were just promoted to the top flight in May and have yet to earn a point this season, but they did beat the Red Devils at Turf Moor in 2009. With no games next weekend, Louis van Gaal will likely be urging his players to go for three points instead of settling for a draw.

Fans do have some positives to rely on going into Saturday’s match. Di Maria is probable to play at some point, while being named England captain could give striker Wayne Rooney a psychological boost. Van Gaal has urged supporters to remain patient, and former captain Gary Neville offered some perspective this week to those frustrated by the results of the past year:

Elsewhere in the Premier League, Manchester City, Swansea, and Chelsea are aiming to continue perfect starts Saturday, against Stoke, West Brom, and at Everton respectively. Like Burnley, QPR looks for a first point when they host Sunderland, and Newcastle welcomes Crystal Palace to St. James’ Park. West Ham United will play Southampton in one of the 10 AM Eastern matches.

On Sunday, Tottenham could go into the two-week break atop the League if they beat Liverpool at White Hart Lane, but the Reds want to get back on track themselves after a Monday night loss at Manchester City.  Aston Villa take on Hull City, while in the final game of the weekend, Leicester hosts Arsenal in a battle between last year’s Championship winners and the FA Cup holders.

The English football season is underway! Who do you think will earn critical wins on Matchday 3?